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Once Wine is installed, you don't "open" Wine; you use it to open your Windows file.

Drag the downloaded .app to your Applications folder. 3. How to Run Your 64-bit .exe Download WEIN 64bit exe

(optional but recommended for many apps): sudo dpkg --add-architecture i386 Update and Install: sudo apt update sudo apt install wine64 Once Wine is installed, you don't "open" Wine;