The plot follows a complex, often confusing, timeline involving ancient biblical figures and a doomed future:
: The film reimagines Cain (of Cain and Abel) and Lilith as the king and queen of a bloodthirsty lineage. Cain seeks a specific astrological moment—the blood moon—where a descendant with his "mark" can finally kill him, ending his immortality.
: Unlike traditional vampires, the creatures in this film often look like humans with red paint bleeding from their eyes.