Grey's Anatomy S16e16 〈PROVEN〉

While the letters dominate the episode, a few other developments occur at Grey Sloan:

He discovered that Izzie used the embryos they froze years ago when she had cancer. Grey's Anatomy s16e16

Izzie has five-year-old twins, Eli and Alexis , who are biologically Alex’s. While the letters dominate the episode, a few

Alex explains she will always be "his person," but he found a reason to stay away that he couldn't ignore. After reading the letter and realizing her marriage

After reading the letter and realizing her marriage is over, Jo heads back to work, determined to stay strong despite the heartbreak. 🗣️ Fan and Critic Reaction

While calling former colleagues to gather support for Meredith’s medical license hearing (earlier in the season), Alex reached out to Izzie .

The central twist of the episode is that Alex has reunited with his ex-wife, .