In the psychological horror game Pathologic , Anna Angel is one of the "Bound" characters—those whose lives are tied to the protagonist's success. She is a former opera singer living in the "Verba" house, and she is widely considered one of the town’s most morally ambiguous and paranoid residents.

A central mystery of her character involves her rivalry with Willow Mellow. Some players theorize Anna may have swapped identities or bodies with Willow in the past to escape her "ugly" origins.

If you are referring to the 1944 children's book The Christmas Anna Angel by Ruth Sawyer, it is a heartwarming story set in Hungary during World War II. The Christmas Anna Angel | Don't read this to my kids