Alpha Fetoprotein -

1. Alpha-Fetoprotein (AFP) in Pregnancy (Prenatal Screening)

It is a screening test, not a diagnostic one. A positive screen does not mean a definite abnormality; further diagnostics, such as an ultrasound or amniocentesis, are usually required. 2. Alpha-Fetoprotein (AFP) as a Tumor Marker Alpha-Fetoprotein (AFP) Test: MedlinePlus Medical Test alpha fetoprotein

Alpha-fetoprotein (AFP) is a protein produced primarily by the liver and yolk sac of a developing fetus during pregnancy. While levels are high in fetuses and decrease significantly by age 1, AFP testing is used in two distinct medical contexts: prenatal screening and tumor marker monitoring. Elevated AFP levels may indicate neural tube defects

Elevated AFP levels may indicate neural tube defects (such as spina bifida or anencephaly), abdominal wall defects, twin pregnancy, or an incorrectly estimated gestational age. abdominal wall defects

Lower than normal levels may indicate Down syndrome (trisomy 21) or Edwards syndrome (trisomy 18).