Agammaglobulinemia

: It is most commonly caused by mutations in the BTK gene , which is essential for B cell development. Common Types

: Patients have a "pan-hypogammaglobulinemia," meaning all major classes of antibodies (IgG, IgA, IgM) are nearly absent. agammaglobulinemia

: A rarer form that can affect both males and females, caused by mutations in other genes like IGHM or CD79A . Symptoms & Complications : It is most commonly caused by mutations

: The body fails to develop mature B lymphocytes, which are the white blood cells responsible for creating antibodies. agammaglobulinemia