This specific update focused heavily on hardware compatibility and stability:
Ableton Live 10.1.25 (x64) remains a highly stable and capable version of the Suite, particularly for users on older Windows systems or those prioritizing lightweight performance over the features of newer versions. Technical Overview 10.1.25 (Final maintenance update for Live 10). Architecture: 64-bit only (enabling use of 4GB+ RAM). Target OS: Windows 7, 8, or 10. Ableton – Live Suite 10.1.25 x64
Introduced Apple Metal support for macOS users, though the Windows x64 version benefited from general UI optimizations. Ableton – Live Suite 10.1.25 x64
Added native support for the M-Audio Oxygen Pro series. Ableton – Live Suite 10.1.25 x64
As a late-stage version of 10.1, it includes all the pivotal features from that cycle: Live 10 Release Notes | Ableton