: For fragile molecules, the system uses lower voltages. If you select the "Fragile Ions" setting, never select High Sensitivity as the Slicer Mode.

Before running the system, ensure the laboratory environment meets the specific electrical and spatial requirements:

: Install 1 liter of 100% LCMS-grade deionized water (Channel A) and 1 liter of 100% LCMS-grade methanol (Channel B).

: The 6546 model uses 10 GHz as the only calibration mode.

: You can save and load custom window layouts (e.g., hiding calibration curves) to streamline your workflow.

: Use the Agilent Site Preparation Checklist to verify all supplies and utilities are ready. 2. System Checkout and Conditioning

The system is managed through software: