39091.mp4

: Showing the progression of a cell through mitosis.

: It helps regulate the organization and stability of the mitotic spindle , the machinery that pulls chromosomes apart during cell division. 39091.mp4

: Without proper Chmp4c function, cells often experience errors in chromosome alignment, leading to genomic instability. : Showing the progression of a cell through mitosis

: Visualizing how the spindle forms and interacts with chromosomes in both control cells and Chmp4c-depleted cells to illustrate the paper's findings. 39091.mp4

The study investigates the role of , a protein traditionally known for its function in the ESCRT-III (Endosomal Sorting Complex Required for Transport) pathway, which typically handles late-stage cell division (abscission). The researchers discovered that Chmp4c has a much earlier role: