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Research from Genes & Development highlights that miR-140 protects against osteoarthritis. It does this by regulating specific genes like ADAMTS5 , which is responsible for breaking down the cartilage matrix.
MicroRNA-140 is highly expressed in cartilage and is a master regulator of chondrocytes (the cells responsible for cartilage formation).
Because its levels fluctuate heavily depending on the presence of tumors, tracking miR-140 expression quantities in tissue is actively researched as a way to predict clinical outcomes and survival rates in patients with neoplasia.
A breakthrough study published in Nature discovered that a "gain-of-function" mutation in the miR-140 gene leads to a severe, novel autosomal dominant human skeletal dysplasia. 🔬 Function in Cancer and Therapeutics
Research from Genes & Development highlights that miR-140 protects against osteoarthritis. It does this by regulating specific genes like ADAMTS5 , which is responsible for breaking down the cartilage matrix.
MicroRNA-140 is highly expressed in cartilage and is a master regulator of chondrocytes (the cells responsible for cartilage formation). 140 РђРЅРѕРЅСЃ
Because its levels fluctuate heavily depending on the presence of tumors, tracking miR-140 expression quantities in tissue is actively researched as a way to predict clinical outcomes and survival rates in patients with neoplasia. Research from Genes & Development highlights that miR-140
A breakthrough study published in Nature discovered that a "gain-of-function" mutation in the miR-140 gene leads to a severe, novel autosomal dominant human skeletal dysplasia. 🔬 Function in Cancer and Therapeutics 140 РђРЅРѕРЅСЃ